NEO214 Is A Mediator of Cell Death Through The Death Receptor Pathway
The Rolipram–Perillyl Alcohol Conjugate (NEO214) Is A Mediator of Cell Death through the Death Receptor Pathway
Authors: Hee-Yeon Cho1,Thu Zan Thein1,WeijunWang1, StephenD. Swenson1, Rochelle A. Fayngor1, Mengting Ou2, Nagore I. Marín-Ramos1, Axel H. Sch€onthal3, Florence M. Hofman1,4, and Thomas C. Chen1,4
This publication shows how NEO214 has great therapeutic potential, especially for brain tumors as the drug can cross the blood-brain barrier, and is effective in the TRAIL-rich astrocyte microenvironment. NEO214 is a strong candidate for use in the treatment of GBMs.