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Publications - NEO 212

NEO-212 Shows Promise In Treating Acute Myeloid Leukemia

NEO-212 Shows Promise In Treating Acute Myeloid Leukemia

Potentially Curative Therapeutic Activity of NEO212, a Perillyl Alcohol-Temozolomide Conjugate, in Preclinical Cytarabine-Resistant Models of Acute Myeloid Leukemia. Authors: Axel H. Schönthal 1, Steve Swenson2, Radu O. Minea2, Hye Na Kim3, Heeyeon Cho2, Nazleen...

Understanding The Pharmacokinetic Properties Of NEO 212

Understanding The Pharmacokinetic Properties Of NEO 212

Pharmacokinetic Properties of the Temozolomide Perillyl Alcohol Conjugate (NEO212) in Mice. Authors: Thomas C Chen, M.D., PhD 1,4, Hee-Yeon Cho1, Steve Swenson1, Thu Zan Thein1, Weijun Wang1, Neloni R. Wijeratne2, Nagore I. Marín-Ramos1, Jonathan E. Katz2, Florence M....

NEO 212 Inhibits Migration and Invasion of Glioma Stem Cells

NEO 212 Inhibits Migration and Invasion of Glioma Stem Cells

A Novel Temozolomide–Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells In Vitro and Intracranial Triple-Negative Tumor Growth In Vivo. Authors: Thomas C. Chen1,2, Hee-Yeon Cho1, Weijun Wang1, Manasai Barath3, Natasha Sharma4, Florance...