Publications - NEO 100
Postsurgical Biopsy Shows Viability of NEO 100 Internasal Delivery
Detection of Perillyl Alcohol and Its Metabolite Perillic Acid in Postsurgical Glioblastoma Tissue After Intranasal Administration of NEO100 Authors: Axel H. Sch€onthal, PhD,1, Steve Swenson, PhD,2, Phillip A. Bonney, MD,2, Naveed Wagle, MD,3, Vincent F. Simmon,...
NEO-100 Enhances Delivery Of Herceptin For Treatment Of Metastatic Breast Cancer In The Brain
Enhanced Brain Delivery And Therapeutic Activity Of Trastuzumab After Blood-Brain Barrier Opening By NEO100 In Mouse Models Of Brain-Metastatic Breast Cancer. Authors: Weijun Wang† 1, Haiping He†5, Nagore I. Marín-Ramos1, Shan Zeng5, Steven D. Swenson1, Hee-Yeon Cho1,...
NEO 100 Human Trial In Adult Patients With Recurrent Glioblastoma
Phase 1 Trial Of Intranasal Neo 100, Highly Purified Perillyl Alcohol, In Adult Patients With Recurrent Glioblastoma. Authors: Axel Schonthal, PhD 1, David M Peereboom3, Naveed Wagle4, Rose Lai5, Anna J Mathew6, Kyle M Hurth6, Vincent F Simmon7, Steven P Howard8,...
Further Study Supporting NEO 100’s Ability To Safely Deliver Therapeutics Through The Blood Brain Barrier
NEO100 enables brain delivery of blood-brain barrier impermeable therapeutics. Authors: Weijun Wang1, Nagore I. Marín-Ramos1, Haiping He1,2, Shan Zeng1,2, Hee-Yeon Cho1, Stephen D. Swenson1, Long Zheng3, Alan L. Epstein3, Axel H. Schönthal4, Florence M....
Improving Therapeutic Efficacy For Brain-Based Cancers Using NEO 100
NEO 100 Enables Brain Delivery Of Blood-Brain Barrier-Impermeable Therapeutics. Authors: Weijun Wang 1, Nagore I. Marín-Ramos1, Haiping He1,2, Shan Zeng1,2, Hee-Yeon Cho1, Stephen D. Swenson1, Long Zheng3, Alan L. Epstein3, Axel H. Schönthal4, Florence M. Hofman3,...
NEO 100 Enables Noninvasive, Therapeutically Effective Delivery of Pharmaceutical Agents
Efficient brain targeting and therapeutic intracranial activity of bortezomib through intranasal co-delivery with NEO100 in rodent glioblastoma models Authors: Weijun Wang, MD1, Steve Swenson, PhD1, Hee-Yeon Cho, PhD1, Florence M. Hofman, PhD2, Axel H. Schönthal,...